Original Article
Alcohol-containing Mouthwash and Oral Cancer Risk: A Systematic Review
Year: 2015 | Month: September | Volume 2 | Issue 3
1.Hotz PR. Dental plaque control and dental caries. Proceedings of the European Workshop on Mechanical Plaque Control. Chicago: Quintessence; 1998. p. 35-49
View at Google Scholar2.Haq MW, Batool M, Ahsan SH, Qureshi NR. Alcohol use in mouthwash and possible oral health concerns. J Pak Med Assoc 2009;59:186-90.
View at Google Scholar3.Brinkman BM, Wong DT. Disease mechanism and biomarkers of oral squamous cell carcinoma. Curr Opin Oncol 2006;18:228-33.
View at Google Scholar4.Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009;45:309-16.
View at Google Scholar5.Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Bouvard V, et al. Carcinogenicity of alcoholic beverages. Lancet Oncol 2007;8:292-3
View at Google Scholar6.Seitz HK, Stickel F. Molecular mechanisms of alcohol-mediated carcinogenesis. Nat Rev Cancer 2007;7:599-612.
View at Google Scholar7.Weaver A, Fleming SM, Smith DB. Mouthwash and oral cancer: Carcinogen or coincidence? J Oral Surg 1979;37:250-3
View at Google Scholar8.Currie S, Farah CS. Alcohol-containing mouthwash and oral cancer risk: A review of current evidence. OA Alcohol 2014;2:4
View at Google Scholar9.Guha N, Boffetta P, Wünsch Filho V, Eluf Neto J, Shangina O, Zaridze D, et al. Oral health and risk of squamous cell carcinoma of the head and neck and esophagus: Results of two multicentric case-control studies. Am J Epidemiol 2007;166:1159-73.
View at Google Scholar10.Winn DM, Bolt WJ, McLaughlin JK, Austin DF, Greenberg RS, Preston-Martin S, et al. Mouth wash use and oral conditions in the risk of oral and pharyngeal cancer. Cancer Res 1991;51:3044-7
View at Google Scholar11.Howie NM, Trigkas TK, Cruchley AT, Wertz PW, Squier CA, Williams DM. Short-term exposure to alcohol increases the permeability of human oral mucosa. Oral Dis 2001;7:349-54
View at Google Scholar12.WHO International Agency for Research on Cancer. Re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide. IARC Monogr Eval Carcinog Risks Hum 1999;71:1-315.
View at Google Scholar13.Angadi PV, Savitha JK, Rao SS, Sivaranjini Y. Oral fi eld cancerization: Current evidence and future perspectives. Oral Maxillofac Surg 2012;16:171-80.
View at Google Scholar14.Scully C. Cancers of oral mucosa, 2009. Available from: http:// www.emedicine.com/derm/TOPIC565.HTM. Read more about oral cancers of oral mucosa on medscape
View at Google Scholar15.Beyer J, Gerostamoulos D, Drummer O, Costantino A. Comments on “The effect of the use of mouthwash on ethylglucuronide concentration in urine”. J Anal Toxicol 2007;31:294-5
View at Google Scholar16.Wigmore JG, Leslie GM. The effect of swallowing or rinsing alcohol solution on the mouth alcohol effect and slope detection of the intoxilyzer 5000. J Anal Toxicol 2001;25:112-4.
View at Google Scholar17.Wynder EL, Kabat G, Rosenberg S, Levenstein M. Oral cancer and mouthwash use. J Natl Cancer Inst 1983;70:255-60
View at Google Scholar18.Blot WJ, Winn DM, Fraumeni JF Jr. Oral cancer and mouthwash. J Natl Cancer Inst 1983;70:251-3.
View at Google Scholar19.Marshall JR, Graham S, Haughey BP, Shedd D, O’Shea R, Brasure J, et al. Smoking, alcohol, dentition and diet in the epidemiology of oral cancer. Eur J Cancer B Oral Oncol 1992;28B:9-15.
View at Google Scholar20.Marques LA, Eluf-Neto J, Figueiredo RA, Góis-Filho JF, Kowalski LP, Carvalho MB, et al. Oral health, hygiene practices and oral cancer. Rev Saude Publica 2008;42:471-9.
View at Google Scholar21.Eliot MN, Michaud DS, Langevin SM, McClean MD, Kelsey KT. Periodontal disease and mouthwash use are risk factors for head and neck squamous cell carcinoma. Cancer Causes Control 2013;24:1315-22.
View at Google Scholar22.McCullough MJ, Farah CS. The role of alcohol in oral carcinogenesis with particular reference to alcohol-containing mouthwashes. Aust Dent J 2008;53:302-5.
View at Google Scholar23.Rodrigues F, Lehmann M, do Amaral VS, Reguly ML, de Andrade HH. Genotoxicity of three mouthwash products, cepacol, periogard, and plax, in the drosophila wing-spot test. Environ Mol Mutagen 2007;48:644-9
View at Google Scholar24.IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Alcohol consumption and ethyl carbamate. IARC Monogr Eval Carcinog Risks Hum 2010;96:3-1383.
View at Google Scholar25.Secretan B, Straif K, Baan R, Grosse Y, El Ghissassi F, Bouvard V, et al. A review of human carcinogens – Part E: Tobacco, areca nut, alcohol, coal smoke, and salted fi sh. Lancet Oncol 2009;10:1033-4
View at Google Scholar26.Lachenmeier DW, Gumbel-Mako S, Sohnius EM, Keck-Wilhelm A, Kratz E, Mildau G. Salivary acetaldehyde increase due to alcohol containing mouthwash use: A risk factor for oral cancer. Int J Cancer 2009;125:730-5.
View at Google Scholar27.Gandini S, Negri E, Boffetta P, La Vecchia C, Boyle P. Mouthwash and oral cancer risk quantitative meta-analysis of epidemiologic studies. Ann Agric Environ Med 2012;19:173-80
View at Google Scholar28.Nummi KP, Salaspuro M, Vakevainen S. The use of alcoholcontaining mouthwash leads to production of carcinogenic acetaldehyde in the oral cavity. Alcohol Alcohol 2011;46:43.
View at Google Scholar29.Moazzez R, Thompson H, Palmer RM, Wilson RF, Proctor GB, Wade WG. Effect of rinsing with ethanol-containing mouth rinses on the production of salivary acetaldehyde. Eur J Oral Sci 2011;119:441-6.
View at Google Scholar30.La Vecchia C. Mouthwash and oral cancer risk: An update. Oral Oncol 2009;45:198-200
View at Google Scholar31.Winn DM, Diehl SR, Brown LM, Harty LC, Bravo-Otero E, Fraumeni JF Jr, et al. Mouthwash in the etiology of oral cancer in Puerto Rico. Cancer Causes Control 2001;12:419-29.
View at Google Scholar32.Cole P, Rodu B, Mathisen A. Alcohol-containing mouthwash and oropharyngeal cancer: A review of the epidemiology. J Am Dent Assoc 2003;134:1079-87.
View at Google Scholar33.Mashberg A, Barsa P, Grossman ML. A study of the relationship between mouthwash use and oral and pharyngeal cancer. J Am Dent Assoc 1985;110:731-4
View at Google Scholar34.Young TB, Ford CN, Brandenburg JH. An epidemiologic study of oral cancer in a statewide network. Am J Otolaryngol 1986;7:200-8
View at Google Scholar35.Kabat GC, Hebert JR, Wynder EL. Risk factors for oral cancer in women. Cancer Res 1989;49:2803-6
View at Google Scholar36.Macfarlane TV, Macfarlane GJ, Oliver RJ, Benhamou S, Bouchardy C, Ahrens W, et al. The aetiology of upper aerodigestive tract cancers among young adults in Europe: The ARCAGE study. Cancer Causes Control 2010;21:2213-21.
View at Google Scholar37.Talamini R, Vaccarella S, Barbone F, Tavani A, La Vecchia C, Herrero R, et al. Oral hygiene, dentition, sexual habits and risk of oral cancer. Br J Cancer 2000;83:1238-42
View at Google Scholar38.Divaris K, Olshan AF, Smith J, Bell ME, Weissler MC, Funkhouser WK, et al. Oral health and risk for head and neck squamous cell carcinoma: The Carolina Head and Neck Cancer Study. Cancer Causes Control 2010;21:567-75.
View at Google Scholar39.Chang JS, Lo HI, Wong TY, Huang CC, Lee WT, Tsai ST, et al. Investigating the association between oral hygiene and head and neck cancer. Oral Oncol 2013;49:1010-7
View at Google Scholar40.Elmore JG, Horwitz RI. Oral cancer and mouthwash use: Evaluation of the epidemiologic evidence. Otolaryngol Head Neck Surg 1995;113:253-61
View at Google Scholar41.Carretero Peláez MA, Esparza Gómez GC, Figuero Ruiz E, Cerero Lapiedra R. Alcohol-containing mouthwashes and oral cancer. Critical analysis of literature. Med Oral 2004;9:120-3, 116-20
View at Google Scholar42.Lewis M, Murray S. Safety of alcohol-containing mouthwashes. A review of the evidence. Dent Health 2006;45:2-4.
View at Google Scholar43.Warnakulasuriya S. Causes of oral cancer – An appraisal of controversies. Br Dent J 2009;207:471-5.
View at Google Scholar44.Settembrini L, Penugonda B, Scherer W, Strassler H, Hittelman E. Alcohol-containing mouthwasheses: Effect on composite color. Oper Dent 1995;20:14-7
View at Google Scholar45.Weiner R, Millstein P, Hoang E, Marshall D. The effect of alcoholic and nonalcoholic mouthwashes on heat-treated composite resin. Oper Dent 1997;22:249-53.
View at Google Scholar46.Salaspuro M. Interrelationship between alcohol, smoking, acetaldehyde and cancer. Novartis Found Symp 2007;285:80-9
View at Google Scholar47.McCullogh M, Prasad G, Zhao S, Farah C. The changing aetiology of oral cancer and the role of novel biomarkers to aid in early diagnosis. In: Ogbureke KU, editor. Oral Cancer. Rijeka: In Tech; 2012. p. 130-48.
View at Google Scholar48.D’Souza G, Kreimer AR, Viscidi R, Pawlita M, Fakhry C, Koch WM, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 2007;356:1944-56.
View at Google Scholar49.Shapiro S, Castellana JV, Sprafka JM. Alcohol-containing mouthwashes and oropharyngeal cancer: A spurious association due to underascertainment of confounders? Am J Epidemiol 1996;144:1091-5
View at Google Scholar50.Eugeniu MC, Radu C, Vlad P. Chlorhexidine as endodontic cleaning solution compared to sodium hypochlorite: An in vivo study. Int J Dent Med Spec 2015;2(1):2-6.
View at Google Scholar51.Lemos CA Jr, Villoria GE. Reviewed evidence about the safety of the daily use of alcohol-based mouthrinses. Braz Oral Res 2008;22:24-31.
View at Google Scholar